Fragile X syndrome
Fragile X syndrome is the second most common specific cause of learning disability after Downs Syndrome. It affects 1 in 1000 males. A milder form affects 1 in 2500 girls who may have normal intelligence.
It is associated with a typical appearance that includes an elongated face, long and prominent ears and a large head circumference.
It is also associated with physical problems such as mitral valve prolapse, joint laxity, spinal scoliosis and flat feet.
80% have learning disability, which is usually mild to moderate.
Features of Fragile X syndrome include abnormalities of speech and language, problems with attention and concentration, difficulty adjusting to change [particularly environmental change] and mood instability.
Boys tend to have more behavioural problems than girls and tend to be shy and socially withdrawn. Girls often suffer from anxiety and depression. It is associated with autism and ADHD.
Behavioural problems are common and tend to improve with age.
Some people with Fragile X syndrome live independently and are in mainstream employment. However the majority require supported accommodation and supported employment.
Care and mobility needs therefore vary according to the severity of the condition and the associated learning disability.
Amended Ocober 2012
