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Prognosis and duration of disabling effects

Urticaria does not usually cause significant functional restrictions.

Once it has developed, allergic sensitisation tends to persist for life and the urticarial reaction can recur with any exposure to the relevant allergen. In many cases, a degree of tolerance can develop and the condition may resolve spontaneously. Where sensitivity is due to a known agent that can be avoided, such as a particular drug, the condition may never recur.